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Более 40 научных работ подтверждают эффективность и безопасность экстракта Джимнемы при сахарном диабете.

О действии комплекса для снижения сахара в крови по Системе Соколинского, который используется в Центре Соколинского в Праге можно прочитать здесь.

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Главным действующим компонентом является экстракт Джимнемы Сильвестра. Ниже список научных работ, посвященных этому растению.

 

  1. Ananthan, R., Latha, M., Pari, L., Ramkumar, K. M., Baskar, C. G., and Bai, V. N. Effect of Gymnema montanum on blood glucose, plasma insulin, and carbohydrate metabolic enzymes in alloxan-induced diabetic rats. J Med Food 2003;6 (1):43-49. View abstract.

  2. Baskaran, K, Ahamath, BK, Shanmugasundaram, KR, and et all. Antidiabetic effect of a leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients. J Ethnopharm 1990;30:295-305.

  3. Bishayee, A and Chatterjee, M. Hypolipidaemic and antiatherosclerotic effects of oral gymnema sylvestre R. Br. leaf extract in albino rats fed a high fat diet. Phytother Res 1994;8:118-120.

  4. Brala, P and Hagen, R. Effects of sweetness perception and caloric value of a preload on short term intake. Physiol Behav 1983;30:1-9.

  5. Chattopadhyay RR. Possible mechanism of antihyperglycemic effect of Gymnema sylvestre leaf extract, Part I. Gen Pharm 1998;31 (3):495-496.

  6. Gholap, S. and Kar, A. Effects of Inula racemosa root and Gymnema sylvestre leaf extracts in the regulation of corticosteroid induced diabetes mellitus: involvement of thyroid hormones. Pharmazie 2003;58 (6):413-415. View abstract.

  7. Gupta SS and Variyar MC. Experimental studies on pituitary diabetes IV. Effect of Gymnema sylvestre and Coccinia indica against the hyperglycemia response of somatotrophin and corticotrophin hormones. Indian J Med Res 1964;52:200-207.

  8. Imoto, T, Miyasaka, A, Ishima, R, and et all. A novel peptide isolated from the leaves of Gymnema sylvestre — I. Characterization and its suppressive effect on the neural responses to sweet taste stimuli in the rat. Comp Biochem Physiol A 1991;100 (2):309-314.

  9. Jiang, H. [Advances in the study on hypoglycemic constituents of Gymnema sylvestre (Retz.) Schult]. Zhong.Yao Cai. 2003;26 (4):305-307. View abstract.

  10. Kamei, K, Takano, R, Miyasaka, A, and et al. Amino acid sequence of sweet-taste-suppressing peptide (gurmarin) from the leaves of Gymnema sylvestre. J Biochem 1992;111:109-112.

  11. Khare AK, Tondon RN, and Tewari JP. Hypoglycaemic activity of an indigenous drug (Gymnema sylvestre, «Gurmar») in normal and diabetic persons. Indian J Physiol Pharm 1983;27:257-258.

  12. Koch RB, Desaiah D, and Cutkomp LK. Inhibition of ATPases by gymnemic acid. Chem Biol Interact 1973;7:121-125.

  13. Kothe A and Uppal R. Antidiabetic effects of Gymnema sylvestre in NIDDM — a short study. Indian J Homeopath Med 1997;32 (1-2):61-62, 66.

  14. Lawless, H. T. Evidence for neural inhibition in bittersweet taste mixtures. J Comp Physiol Psychol 1979;93 (3):538-547. View abstract.

  15. Murakami, N, Murakami, T, Kadoya, M, and et all. New hypoglycemic constituents in «gymnemic acid» from Gymnema sylvestre. Chem Pharm Bull 1996;44 (2):469-471.

  16. Okabayashi, Y., Tani, S., Fujisawa, T., Koide, M., Hasegawa, H., Nakamura, T., Fujii, M., and Otsuki, M. Effect of Gymnema sylvestre, R.Br. on glucose homeostasis in rats. Diabetes Res Clin Pract 1990;9 (2):143-148. View abstract.

  17. Porchezhian, E. and Dobriyal, R. M. An overview on the advances of Gymnema sylvestre: chemistry, pharmacology and patents. Pharmazie 2003;58 (1):5-12. View abstract.

  18. Preuss HG, Jarrell ST, Scheckenbach R, and et al. Comparative effects of chromium, vanadium and gymnema sylvestre on sugar-induced blood pressure elevations in SHR. J Amer Coll Nutrit 1998;17 (2):116-123.

  19. Preuss, H. G., Garis, R. I., Bramble, J. D., Bagchi, D., Bagchi, M., Rao, C. V., and Satyanarayana, S. Efficacy of a novel calcium/potassium salt of (-)-hydroxycitric acid in weight control. Int.J Clin.Pharmacol.Res. 2005;25 (3):133-144. View abstract.

  20. Rathi AN, Visvanathan A, and Shanmugasundaram KR. Studies on protein-bound polysaccharide components & glycosaminoglycans in experimental diabetes — effect of Gymnema sylvestre, R.Br. Indian J Exper Biol 1981;19:715-721.

  21. Shanmugasundaram ERB, Gopinath KL, Shanmugasundaram KR, and et al. Possible regeneration of the islets of Langerhans in streptozotocin-diabetic rats given Gymnema sylvestre leaf extracts. J Ethnopharm 1990;30:265-279.

  22. Shanmugasundaram ERB, Rajeswari G, Baskaran K, and et al. Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin-dependent diabetes mellitus. J Ethnopharm 1990;30 (3):281-294.

  23. Shanmugasundaram KR, Panneerselvam C, Samudram P, and et al. Enzyme changes and glucose utilisation in diabetic rabbits: the effect of Gymnema sylvestre, R.Br. J Ethnopharm 1983;7:205-234.

  24. Sinsheimer JE, Rao GS, and McIlhenny HM. Constituents from Gymnema sylvestre leaves V. Isolation and preliminary characterization of the gymnemic acids. J Pharm Sci 1970;59 (5):622-628.

  25. Srivastava Y, Bhatt HV, Prem AS, and et al. Hypoglycemic and life-prolonging properties of Gymnema sylvestre leaf extract in diabetic rats. Israel J Med Sci 1985;21:540-542.

  26. Terasawa H, Miyoshi M, and Imoto T. Effects of long-term administration of Gymnema sylvestre watery-extract on variations of body weight, plasma glucose, serum triglyceride, total cholesterol and insulin in Wistar fatty rats. Yonago Acta Med 1994;37:117-127.

  27. Tominaga M, Kimura M, Sugiyama K, and et al. Effects of seishin-renshi-in and Gymnema sylvestre on insulin resistance in streptozotocin-induced diabetic rats. Diabet Res Clin Pract 1995;29:11-17.

  28. Wang LF, Luo H, Miyoshi M, and et al. Inhibitory effect of gymnemic acid on intestinal absorption of oleic acid in rats. Can J Physiol Pharmacol 1998;76:1017-1023.

  29. Xie, J. T., Wang, A., Mehendale, S., Wu, J., Aung, H. H., Dey, L., Qiu, S., and Yuan, C. S. Anti-diabetic effects of Gymnema yunnanense extract. Pharmacol Res 2003;47 (4):323-329. View abstract.

  30. Ye, W., Liu, X., Zhang, Q., Che, C. T., and Zhao, S. Antisweet saponins from Gymnema sylvestre. J Nat.Prod. 2001;64 (2):232-235. View abstract.

  31. Yoshikawa, M., Murakami, T., Kadoya, M., Li, Y., Murakami, N., Yamahara, J., and Matsuda, H. Medicinal foodstuffs. IX. The inhibitors of glucose absorption from the leaves of Gymnema sylvestre R. BR. (Asclepiadaceae): structures of gymnemosides a and b. Chem.Pharm Bull. (Tokyo) 1997;45 (10):1671-1676. View abstract.

  32. Ananthan R, Baskar C, NarmathaBai V, et al. Antidiabetic effect of Gymnema montanum leaves: effect on lipid peroxidation induced oxidative stress in experimental diabetes. Pharmacol Res 2003;48:551-6. View abstract.

  33. Baskaran K, Kizar Ahamath B, Radha Shanmugasundaram K, Shanmugasundaram ER. Antidiabetic effect of leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients. J Ethnopharmacol 1990;30:295-300. View abstract.

  34. Head KA. Type 1 diabetes: prevention of the disease and its complications. Townsend Letter for Doctors & Patients 1998;180:72-84.

  35. Katsukawa H, Imoto T, Ninomiya Y. Induction of salivary gurmarin-binding proteins in rats fed gymnema-containing diets. Chem Senses 1999;24:387-92. View abstract.

  36. Luo H, Kashiwagi A, Shibahara T, Yamada K. Decreased bodyweight without rebound and regulated lipoprotein metabolism by gymnemate in genetic multifactor syndrome animal. Mol Cell Biochem 2007;299:93-8. View abstract.

  37. Persaud SJ, Al-Majed H, Raman A, Jones PM. Gymnema sylvestre stimulates insulin release in vitro by increased membrane permeability. J Endocrinol 1999;163:207-12. View abstract.

  38. Preuss HG, Bagchi D, Bagchi M, et al. Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes Obes Metab 2004;6:171-180. View abstract.

  39. Satdive RK, Abhilash P, Fulzele DP. Antimicrobial activity of Gymnema sylvestre leaf extract. Fitoterapia 2003;74:699-701. View abstract.

  40. Shanmugasundaram ER, Rajeswari G, Baskaran K, et al. Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin-dependent diabetes mellitus. J Ethnopharmacol 1990;30:281-94. View abstract.

  41. Sinsheimer JE, Subba-Rao G, McIlhenny HM. Constitents from G sylvestre leaves: isolation and preliminary characterization of the gymnemic acids. J Pharmacol Sci 1970;59:622-8.

  42. Yeh GY, Eisenberg DM, Kaptchuk TJ, Phillips RS. Systematic review of herbs and dietary supplements for glycemic control in diabetes. Diabetes Care 2003;26:1277-94. View abstract.